Presented as a poster at the AzCEP Annual Scientific Assembly, this study evaluates oxygenation during rapid sequence intubation under complete paralysis and no ventilation.
Across a structured large-animal series, serial arterial blood gases were obtained during prolonged apnea (up to 16 minutes). Under control conditions, oxygen saturation declined rapidly, falling below 75% in under one minute.
In contrast, when oxygen was delivered at the glottic inlet, arterial blood gas analysis demonstrated sustained oxygenation despite the absence of spontaneous respiration. Oxygen levels remained stable throughout the apnea period, while carbon dioxide increased gradually, consistent with expected physiologic patterns in non-ventilated states.
These findings emphasize the impact of oxygen delivery location. Conventional nasal oxygen delivery occurs at a distance from the vocal cords, whereas targeted delivery at the glottic inlet is reflected directly in arterial oxygenation measurements.
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View the presentation using this link.https://sharpmed.com/wp-content/uploads/2026/04/AzCEP-Research-Symposium-Poster-Presentation-2026.pdf
Airway Oxygenation Brief (20-Min Clinical Discussions)
We are hosting short, clinician-led discussions focused on oxygenation during intubation – specifically where traditional approaches can fall short and how targeted airway oxygenation is being explored in practice.
These sessions are practical and discussion-based, bringing together perspectives from emergency, ICU, respiratory care, and EMS settings.
If interested, you can add an upcoming session directly to your calendar: https://sharpmed.com/live-series/
Thursdays | 11:30 AM EST | 20 min | Join live
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630-232-8002 x1 | orders@sharpmed.com